Clinical Programs

We have established a portfolio of proprietary product development programs that includes both biologics and pharmaceuticals. Our most advanced programs are in the area of regenerative medicine, applying our patented and proprietary stem cell product, MultiStem®, that we believe has potential for treating multiple disease conditions, including in the neurological, cardiovascular, inflammatory and immune disease areas. Over the past several years, we have advanced MultiStem programs to clinical development stage and established preclinical programs through our internal efforts and broad network of collaborations across the United States and Europe. We believe that our pipeline can be broadened over time, driven by our technologies, capabilities and approach. In addition to our programs in regenerative medicine, we are also applying our other technologies and capabilities to develop new pharmaceutical based treatments for obesity, related metabolic conditions and certain neurological disorders.



Overview/Pipeline

We are developing MultiStem®, a patented, adult-derived “off-the-shelf” stem cell product platform, for multiple disease indications in the areas of  neurological, cardiovascular and inflammatory & immune disease areas.


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Neurological

In collaboration with leading stroke treatment centers in the U.S. and the United Kingdom, we recently reported initial results from a double blind, placebo controlled Phase 2 clinical trial evaluating the safety and efficacy of MultiStem® administered intravenously to ischemic stroke victims.


Stroke Phase II

Cardiovascular

We are currently conducting a Phase 2 clinical trial to evaluate the safety and efficacy of MultiStem administered to patients that have suffered significantly impaired heart function due to a heart attack (myocardial infarction).


AMI Phase II

Inflammatory & Immune

We have explored/ are evaluating MultiStem for the treatment of multiple disease indications in the inflammatory and immune disease areas, including Acute Respiratory Distress Syndrome(ARDS), Inflammatory Bowel Disease(IBD) and others.


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